
Did you know that there are inherited biological codes that are NOT stored in DNA and that are NOT epigenetic modification on DNA?
I’m excited to announce that we have updated my paper describing Heritable Nongenetic Information (HNI, pronounced “honey”), a concept that describes various types of codes in biology that are inherited but are not stored in DNA.
We refined the definition of HNI and included a figure and table showing the difference between HNI and previous concepts, such as: Nongenetic Information (NGI) which includes transmitted molecules and taught behaviors; and Inherited Gene Regulation (IGR), which refers to epigenetic modifications.
We also added a section explaining the benefits of cracking 2D and 3D codes for biomedical discoveries.
Most of the paper provides evidence for the “Tissue Spatial Code” that affects wound healing, limb regeneration, and cancer development apart from the instructions in DNA. We also provide evidence of HNI that affects protein structure.
The preprint is hosted ArXiv, but a PDF is here:
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